Healthcare

Illumina, Inc. (ILMN)

$162.55
-1.13%
$24.7B
Market Cap
29.6
P/E Ratio
1.42
Beta
Dividend Yield
Piotroski 7/9Altman Z 4.3 SafeBeneish M -2.50 CleanROIC−WACC +5.3%

Quantitative Summary

Deterministic

At 29.6x earnings — a 55% discount to the sector average of 65.2x — ILMN is in the lower valuation range. Financial health metrics are strong: Piotroski 7/9, Altman Z 4.3 (above 3.0 safe zone threshold). DCF fair value of $108 implies 15% downside based on model assumptions.

Generated deterministically from quant metrics and financial statements. Not a recommendation.

Algorithmic Teardown

AI-Generated

Illumina demonstrates robust capital efficiency with an ROIC of 18.5% significantly exceeding its WACC of 13.3%, generating a +5.2% spread that indicates strong value creation potential despite recent revenue contraction of -0.7%. The DuPont decomposition reveals this return is driven primarily by high net margins at 19.6% and elevated leverage via an equity multiplier of 2.44x, rather than asset turnover which sits modestly at 0.65x. Credit metrics further underscore financial stability; the Altman Z-Score of 4.4 signals a low probability of bankruptcy while the Beneish M-Score of -2.50 suggests earnings are unlikely to be manipulated, and a Piotroski F-Score of 7/9 reflects strong fundamental quality relative to peers.

Valuation analysis presents a divergence between market pricing and intrinsic value models. While the current P/E multiple of 23.4x trades at a discount to the sector average of 36.8x, suggesting some mean reversion has occurred, the DCF fair value calculation implies a -13.4% downside from current levels based on an assumed ten-year free cash flow growth rate of 17.5%. This discrepancy indicates that while the stock appears cheap relative to historical sector norms, specific model inputs regarding future cash generation may not yet be fully reflected in the price or could imply over-optimism about long-term expansion capabilities given the recent revenue decline.

Risk factors appear elevated by factor-based metrics and insider activity. The security exhibits negative Fama-French alpha of -8.48% annually, accompanied by a Value Factor (HML) of -0.462 indicating a growth tilt that has underperformed value strategies, alongside a Profitability Factor (RMW) delta of -0.764 highlighting weak profitability relative to the factor universe. Compounding these quantitative signals is insider flow data showing $407,001 in net selling over the past 90 days, which aligns with the negative momentum factors and warrants close monitoring for potential capital preservation concerns among management or major shareholders.

Generated by LLM from quantitative data inputs. May contain inaccuracies. Not investment advice.

DCF Sandbox

Interactive
Market Price
$162.55
Fair Value
$107
Implied Upside
-34.4%
$107IMPLIED FAIR VALUEOVERVALUEDOVERUNDER
Growth Rate (Y1–5)17%
-10%20%50%
Discount Rate (WACC)13.2%
5%12.5%20%

5-year two-stage DCF. Terminal growth 3%. Default sliders match the pre-computed base case. Drag to explore scenarios. Not investment advice.

Reverse DCFMarket-Implied
17.8%annual FCF growth priced in at $162.55

The growth rate the market implicitly expects over the next 10 years to justify today's price. Compare with historical growth of -1% YoY revenue.

Sensitivity Matrix

TG ↓ / WACC →11.2%13.2%15.2%
2%$125$100$83
3%$137$108$88
4%$153$117$94

Center = base case. Green = >10% upside, Red = >10% downside vs $162.55.

Pre-computed DCF: WACC=13.2%, terminal growth 3%. Fair value $108 (-15.1%). Not investment advice.

Valuation Context

29.6x
ILMN P/E
65.2x
Sector Avg
43.0x
5Y Avg P/E
-55%
vs Sector

Currently trading 48% below its 5-year average P/E of 43.0x.

Price Chart with Moving Averages

Loading chart...
SMA 50 SMA 200

Technical Setup

AI Generated

The current price level of $144.83 for Illumina, Inc. sits within a context where Short-Term Moving Averages appear to be intersecting with Long-Term counterparts, suggesting a potential shift in momentum that often precedes significant capital rotation. When these averages converge or cross, it frequently indicates that institutional algorithms are recalibrating their exposure based on evolving valuation metrics rather than immediate retail sentiment. The absence of sustained volume expansion accompanying recent price movements may imply that large market participants are currently accumulating positions quietly or waiting for a clearer directional signal before committing substantial liquidity to either side. Institutional positioning often relies heavily on the stability of support levels, and if the stock is holding near these technical thresholds without breaking down, it could suggest defensive accumulation by entities seeking exposure to the healthcare sector at discounted valuations. Conversely, any failure to maintain above critical moving average lines might signal that larger players are reducing leverage or rotating capital toward assets with stronger relative strength profiles. The interplay between price action and volume trends here serves as a barometer for market depth; thin trading alongside volatile swings can indicate uncertainty among sophisticated traders regarding the company's near-term catalysts, while heavy turnover would typically confirm a decisive change in consensus outlook. Ultimately, these technical patterns reflect the dynamic process of large capital reallocating assets rather than providing a definitive direction on future price performance.

RSI (14)
SMA 50
SMA 200

Quant Health Deep Dive

7/9
Piotroski F-Score
Strong — high operational efficiency and profitability signals
4.3
Altman Z-Score
Safe Zone — above 3.0 threshold per academic model. Thresholds: >3 safe, 1.8–3 grey, <1.8 distress.
-2.50
Beneish M-Score
Below threshold — no statistical earnings quality concern per Beneish model. Threshold: <-2.22 = below threshold.

Profitability & Value Creation

66.1%
Gross Margin
19.6%
Net Margin
18.5%
ROIC
13.2%
WACC
ROIC − WACC Spread: +5.3%— Positive value creation spread.
-0.7%
Revenue Growth (YoY)
+169.5%
Earnings Growth (YoY)
931.0M
Free Cash Flow

DuPont Analysis — ROE Decomposition

Breaking down Return on Equity to see how the company generates its ROE — efficiency, margins, or leverage.

19.6%
Net Profit Margin
NI ÷ Revenue
×
0.65x
Asset Turnover
Revenue ÷ Assets
×
2.44x
Equity Multiplier
Assets ÷ Equity
=
31.2%
Return on Equity
✅ ROE driven primarily by strong profit margins — a sign of pricing power.

Balance Sheet Health

1.44x
Debt / Equity
2.08x
Current Ratio
11.8x
Interest Coverage
0.0x
Net Debt / EBITDA
5.02%
FCF Yield
1.5B
EBITDA

Insider Activity (Last 90 Days)

Net Insider Flow
$-407,001
Net Selling
1
Buy Transactions
2
Sale Transactions
2026-03-05DHINGRA ANKURGrant$1M
2026-03-05DAVIES SCOTT MSold 2/8 qtrsGrant$750,076
2026-03-05PEGELS KEVIN CARLGrant$810,092
2026-03-05ERICKSEN SCOTT DGrant$412,548
2026-03-05BARNARD STEVENGrant$975,009

Open-market buys vs sells by company insiders. Source: yfinance.

Earnings Surprise History

Q4
✓ Beat
Est: $0.94
Act: $0.97
+3.3%
Q3
✓ Beat
Est: $1.01
Act: $1.19
+17.7%
Q2
✓ Beat
Est: $1.17
Act: $1.34
+14.7%
Q1
✓ Beat
Est: $1.23
Act: $1.35
+9.7%

EPS estimates vs actuals for the most recent reported quarters. Source: yfinance.

Risk Profile

45.4%
Annual Volatility
1.20
Sharpe (1Y)
-0.33
Sharpe (3Y)
-68.9%
Max Drawdown (3Y)
-86.2%
Max Drawdown (5Y)

Sharpe = risk-adjusted return (higher is better). Max drawdown = largest peak-to-trough decline. 1,200+ trading days.

Underwater (Drawdown from Peak)

How far below the all-time high the price has been over time. Deeper = more pain for holders.

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Rolling 60-Day Beta vs S&P 500 (VOO)

How the stock's sensitivity to market moves changes over time. β > 1 = more volatile than the market.

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Rolling Beta Market (β = 1.0)

Fama-French 5-Factor Exposure

Academic factor model decomposition — what's really driving this stock's returns.

0.76
Market β
Mkt-RF
+0.885
Size (SMB)
Small-cap tilt
-0.462
Value (HML)
Growth tilt
-0.764
Profit (RMW)
Weak
+0.758
Invest (CMA)
Conservative
Alpha (annual): -8.48%
R²: 25.0%of variance explained by 5 factors

Fama-French 5-Factor Model. Data: Kenneth French Data Library. Regression over 3 years of daily returns.

Fundamentals

27.5
Forward P/E
2.78
PEG Ratio
9.26
Price/Book
2M
Avg Volume
$165.37
52W High
$78.79
52W Low
97%
52W Range Position

Passive Flow Attribution

ETF Draft Effect
$2.0B
Tracked Passive Exposure
8
ETFs Holding ILMN
0.08%
Avg Weight in ETFs
$2.5T
Total ETF AUM

When investors buy or sell ETFs like ARKG or ARKK, the fund manager is mechanically forced to buy or sell ILMN shares regardless of Illumina, Inc.'s individual fundamentals. We estimate $2.0B of passive capital is structurally linked to ILMN through 8 tracked ETFs. Index rebalances and ETF creation/redemption cycles can create noticeable volume spikes unrelated to company news.

Passive exposure = Σ (ETF AUM × stock weight in ETF) across 8 tracked ETFs. Actual passive ownership is larger (includes mutual funds). Not investment advice.

ETF Contagion Visualizer

Simulate a price drop in Illumina, Inc. to visualize passive redemption contagion across ETFs and collateral stocks.

ILMN Shock
-0%
Est. Passive Redemption
$0
Systemic Risk
STABLE
ILMNEpicenterVTIETFVBETFVXFETFCRSPLow RiskTEMHigh RiskTWSTLow RiskTSLALow RiskTXGLow Risk
ILMN Price Drop (%)0

If Illumina, Inc. (ILMN) experiences a significant drawdown, ETF redemptions can create collateral selling pressure on co-held stocks. Our model identifies CRISPR THERAPEUTICS AG (CRSP) as the most exposed collateral stock, sharing 2 ETFs with ILMN. This is the "Passive Contagion" effect described in the Inelastic Market Hypothesis.

Contagion model based on shared ETF exposure and constituent weights across 19 tracked ETFs. Estimated selling pressure is a simplified model — actual impact depends on market liquidity, ETF redemption mechanics, and market-maker activity.

ILMN Ownership Dynamics

Passive funds hold 1 in every 10 ILMN shares, reducing daily market volatility.

Ticker
ILMN
Total Shares
151M
ETF Lock-Up
10.3%
Display Mode
Total Float Impact
10.3%Locked Float

Illumina, Inc. (ILMN) exerts measurable gravity on the passive index market, currently representing 4.5% of the ARK Genomic Revolution ETF (ARKG) and 1.4% of the ARK Innovation ETF (ARKK). Across 19 tracked ETFs, approximately 16M shares (10.3% of float) are held by passive funds and rarely trade on the open market. This level of passive ownership means index rebalances can create outsized volume events.

Float lock-up computed from 19 ETFs tracked by SecuritiesDB. Actual passive ownership is higher (includes mutual funds, pension funds, etc.).

ILMN Institutional Volume Profile

252-day volume distribution by price level. The Point of Control (POC) marks the price where the most institutional volume transacted — an implicit support/resistance floor.

TICKER
ILMN
PRICE
$162.55
FLOOR (POC)
$98.41
STRENGTH
High
$81$85$90$9410%$98POC 16%$103$107$111$116$12010%$1259%$1297%$1338%$138$142$146$151$155$159$164$162.55
Focus Zone
Point of Control (POC) Support (below price) Resistance (above price) Current Price

The highest-volume price zone for Illumina, Inc. over the past year sits near $98.41 (16% of 252-day volume). The current price of $162.55 trades 65.2% above this institutional floor — a sign of upside momentum, though a pullback to the POC zone is a common reversion target. The highly concentrated volume profile (16% at POC) indicates strong consensus on fair value — institutional participants have repeatedly transacted near this price.

Volume Profile computed from 252 trading days of OHLCV data. Volume allocated to price bins proportionally based on daily high-low range. Not investment advice.

ILMN Capital Efficiency

How efficiently does Illumina, Inc. convert operating profits into free cash? The FCF Conversion ratio measures the gap between accounting earnings and real cash generation.

Free Cash Flow
$931M
EBITDA
$1.5B
FCF Conversion
64%
Reinvestment Rate
36%
64% of EBITDA → Free Cash
0% (cash burn)25% (low)50% (efficient)100% (pure cash)
ROIC
18.5%
ROIC − WACC Spread
5.3%

Illumina, Inc. converts 64% of its EBITDA into free cash flow, an exceptional conversion rate indicating an asset-light business model with minimal capital reinvestment drag. The positive ROIC-WACC spread of 5.3% confirms that reinvested capital creates shareholder value.

Capital efficiency = Free Cash Flow ÷ EBITDA. Reinvestment = (EBITDA − FCF) ÷ EBITDA. Metrics from latest annual filings. Not investment advice.

Fails-to-Deliver (FTD) History

SEC-reported settlement failures. Elevated FTDs can indicate high short-selling pressure, operational settlement issues, or naked shorting activity.

DateFailed SharesClose PriceNotional Value
2026-05-12151$142.51$21,519.01
2026-05-0611$139.07$1,529.77
2026-05-0516$139.37$2,229.92
2026-04-153$130.32$390.96
2026-04-14316$126.96$40,119.36
2026-04-062$127.38$254.76
2026-03-31256$120.81$30,927.36
2026-03-271,080$124.40$134,352
2026-03-2554$125.98$6,802.92
2026-03-24367$123.79$45,430.93
2026-03-1934,132$122.95$4.2M
2026-03-185$120.84$604.2
2026-03-175,765$119.28$687,649.2
2026-03-09725$124.62$90,349.5
2026-03-0548$128.97$6,190.56
2026-03-04309$129.56$40,034.04
2026-03-0352$132.89$6,910.28
2026-03-0220,583$134.46$2.8M
2026-02-252,422$122.90$297,663.8
2026-02-183,739$116.51$435,630.89
2026-02-173,969$116.81$463,618.89
2026-01-2613,833$150.28$2.1M
2026-01-232,919$153.95$449,380.05
2026-01-222,969$152.48$452,713.12
2026-01-212,959$147.17$435,476.03
2026-01-2068$141.65$9,632.2
2026-01-144,824$146.99$709,079.76
2026-01-136,899$145.55$1.0M
2026-01-1219,335$141.07$2.7M
2026-01-08840$150.14$126,117.6

Source: SEC Regulation SHO FTD data. Data is reported with a ~30 day delay. High FTD quantities relative to average daily volume may indicate settlement stress.

Price Correlations

Statistical correlation of daily returns with other stocks. High correlations indicate stocks that move together; negative correlations can offer diversification.

Peer252-Day (1Y)126-Day (6M)Direction
WTGXXNaNNaN
A0.5850.429Moderate
TXG0.5790.430Moderate
MTD0.5720.397Moderate
TMO0.5630.408Moderate
DHR0.5060.299Moderate
IQV0.5010.297Moderate
PACB0.4740.497Moderate
WAT0.4510.284Moderate
VCYT0.4320.347Moderate

Pearson correlation of daily log returns. 252d ≈ 1 trading year. Computed from price history. Not investment advice.

Compare ILMN to Peers

Quant metrics computed deterministically from financial statements and price data. Updated: 2026-06-02.

SecuritiesDB provides programmatic data aggregation for informational purposes only. None of the metrics, summaries, or algorithmic flags constitute a recommendation to buy or sell any security.