Healthcare

Natera, Inc. (NTRA)

$212.73
-2.78%
$32.0B
Market Cap
P/E Ratio
1.57
Beta
Dividend Yield
Piotroski 4/9Altman Z 23.4 SafeBeneish M 0.48 Flag (> −2.22)

Quantitative Summary

Deterministic

Financial health is average: Piotroski 4/9, Altman Z 23.4. DCF fair value of $27 implies 87% downside based on model assumptions. Beneish M-Score of 0.48 exceeds the -2.22 academic threshold — earnings quality may warrant further review.

Generated deterministically from quant metrics and financial statements. Not a recommendation.

Algorithmic Teardown

AI-Generated

The fundamental economics of Natera reveal a stark divergence between aggressive top-line expansion and deteriorating capital efficiency. While revenue growth remains robust at 35.9% year-over-year, supported by healthy gross margins near 64.8%, the company is currently generating negative returns on invested capital (-10.7%) and equity (-12.2%). This poor profitability stems primarily from a -9.0% net margin rather than low asset turnover or excessive leverage, as indicated by the DuPont decomposition. Financial distress signals are further amplified by a Piotroski F-Score of 4/9 and significant insider selling totaling over $123 million in the last ninety days, suggesting management may be concerned about near-term liquidity or valuation despite strong top-line momentum.

Valuation metrics present a substantial disconnect between current market pricing and intrinsic value models derived from discounted cash flow analysis. The stock trades at an implied discount of 86.9% relative to its DCF fair value estimate of $26, which assumes a ten-year free cash flow growth rate of nearly 47.9%. This aggressive growth assumption appears inconsistent with the company's current negative net margins and weak profitability factor score (RMW: -1.203), raising questions about whether the market is pricing in unsustainable expansion or if the DCF inputs reflect overly optimistic terminal conditions compared to sector peers averaging a P/E of 36.8x.

Risk-adjusted performance data highlights significant exposure to growth and momentum factors rather than value or profitability characteristics, with a pronounced tilt toward high-growth securities (Value Factor: -0.411) and poor relative profitability standing out against the broader factor universe. Although the Fama-French alpha stands at an anomalous 42.17% annually, this metric must be viewed in the context of negative earnings and heavy insider distribution, which often precede downside volatility or strategic pivots rather than sustained compounding returns for long-term holders.

Generated by LLM from quantitative data inputs. May contain inaccuracies. Not investment advice.

DCF Sandbox

Interactive
Market Price
$212.73
Fair Value
$27
Implied Upside
-87.5%
$27IMPLIED FAIR VALUEOVERVALUEDOVERUNDER
Growth Rate (Y1–5)36%
-10%20%50%
Discount Rate (WACC)10.0%
5%12.5%20%

5-year two-stage DCF. Terminal growth 3%. Default sliders match the pre-computed base case. Drag to explore scenarios. Not investment advice.

Reverse DCFMarket-Implied
47.9%annual FCF growth priced in at $212.73

The growth rate the market implicitly expects over the next 10 years to justify today's price. Compare with historical growth of 36% YoY revenue.

Sensitivity Matrix

TG ↓ / WACC →8%10%12%
2%$31$25$21
3%$35$27$22
4%$41$30$24

Center = base case. Green = >10% upside, Red = >10% downside vs $212.73.

Pre-computed DCF: WACC=10.0%, terminal growth 3%. Fair value $27 (-86.7%). Not investment advice.

Price Chart with Moving Averages

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SMA 50 SMA 200

Quant Health Deep Dive

4/9
Piotroski F-Score
Average — mixed operational signals
23.4
Altman Z-Score
Safe Zone — above 3.0 threshold per academic model. Thresholds: >3 safe, 1.8–3 grey, <1.8 distress.
0.48
Beneish M-Score
Above threshold — earnings quality may warrant further review per Beneish model. Threshold: <-2.22 = below threshold.

Profitability & Value Creation

64.8%
Gross Margin
-9.0%
Net Margin
-10.7%
ROIC
+35.9%
Revenue Growth (YoY)
-9.3%
Earnings Growth (YoY)
76.1M
Free Cash Flow

DuPont Analysis — ROE Decomposition

Breaking down Return on Equity to see how the company generates its ROE — efficiency, margins, or leverage.

-9.0%
Net Profit Margin
NI ÷ Revenue
×
0.96x
Asset Turnover
Revenue ÷ Assets
×
1.40x
Equity Multiplier
Assets ÷ Equity
=
-12.2%
Return on Equity
Balanced ROE composition across margins, turnover, and leverage.

Balance Sheet Health

0.40x
Debt / Equity
3.39x
Current Ratio
-64.9x
Interest Coverage
0.29%
FCF Yield
-220.5M
EBITDA

Insider Activity (Last 90 Days)

Net Insider Flow
-$123M
Net Selling
0
Buy Transactions
33
Sale Transactions
2026-03-20SHEENA JONATHANSold 3/3 qtrsSale$908,301
2026-03-16RABINOWITZ MATTHEWSold 3/3 qtrsSale$38M
2026-03-16RABINOWITZ MATTHEWSold 3/3 qtrsGrant$2M
2026-03-13CHAPMAN ROWAN ESold 3/3 qtrsSale$23,348
2026-03-10BROPHY MICHAEL BURKESSold 3/3 qtrsSale$160,244

Open-market buys vs sells by company insiders. Source: yfinance.

Earnings Surprise History

Q4
✓ Beat
Est: $-0.66
Act: $-0.50
+24.2%
Q3
✗ Miss
Est: $-0.59
Act: $-0.74
-24.5%
Q2
✗ Miss
Est: $-0.35
Act: $-0.64
-80.7%
Q1
✓ Beat
Est: $-0.53
Act: $0.36
+167.5%

EPS estimates vs actuals for the most recent reported quarters. Source: yfinance.

Risk Profile

57.0%
Annual Volatility
0.80
Sharpe (1Y)
1.10
Sharpe (3Y)
-39.9%
Max Drawdown (3Y)
-77.7%
Max Drawdown (5Y)

Sharpe = risk-adjusted return (higher is better). Max drawdown = largest peak-to-trough decline. 1,200+ trading days.

Underwater (Drawdown from Peak)

How far below the all-time high the price has been over time. Deeper = more pain for holders.

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Rolling 60-Day Beta vs S&P 500 (VOO)

How the stock's sensitivity to market moves changes over time. β > 1 = more volatile than the market.

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Rolling Beta Market (β = 1.0)

Fama-French 5-Factor Exposure

Academic factor model decomposition — what's really driving this stock's returns.

0.91
Market β
Mkt-RF
+0.216
Size (SMB)
Small-cap tilt
-0.411
Value (HML)
Growth tilt
-1.203
Profit (RMW)
Weak
+0.017
Invest (CMA)
Neutral
Alpha (annual): +42.17%
R²: 26.2%of variance explained by 5 factors

Fama-French 5-Factor Model. Data: Kenneth French Data Library. Regression over 3 years of daily returns.

Fundamentals

-590.7
Forward P/E
PEG Ratio
18.22
Price/Book
1M
Avg Volume
$256.36
52W High
$131.81
52W Low
65%
52W Range Position

Passive Flow Attribution

ETF Draft Effect
$2.6B
Tracked Passive Exposure
8
ETFs Holding NTRA
0.10%
Avg Weight in ETFs
$2.5T
Total ETF AUM

When investors buy or sell ETFs like ARKG or IBB, the fund manager is mechanically forced to buy or sell NTRA shares regardless of Natera, Inc.'s individual fundamentals. We estimate $2.6B of passive capital is structurally linked to NTRA through 8 tracked ETFs. Index rebalances and ETF creation/redemption cycles can create noticeable volume spikes unrelated to company news.

Passive exposure = Σ (ETF AUM × stock weight in ETF) across 8 tracked ETFs. Actual passive ownership is larger (includes mutual funds). Not investment advice.

ETF Contagion Visualizer

Simulate a price drop in Natera, Inc. to visualize passive redemption contagion across ETFs and collateral stocks.

NTRA Shock
-0%
Est. Passive Redemption
$0
Systemic Risk
STABLE
NTRAEpicenterVTIETFVBETFVXFETFCRSPLow RiskTEMHigh RiskTWSTLow RiskTSLALow RiskBEAMLow Risk
NTRA Price Drop (%)0

If Natera, Inc. (NTRA) experiences a significant drawdown, ETF redemptions can create collateral selling pressure on co-held stocks. Our model identifies CRISPR THERAPEUTICS AG (CRSP) as the most exposed collateral stock, sharing 3 ETFs with NTRA. This is the "Passive Contagion" effect described in the Inelastic Market Hypothesis.

Contagion model based on shared ETF exposure and constituent weights across 15 tracked ETFs. Estimated selling pressure is a simplified model — actual impact depends on market liquidity, ETF redemption mechanics, and market-maker activity.

NTRA Ownership Dynamics

Passive funds hold 1 in every 12 NTRA shares, reducing daily market volatility.

Ticker
NTRA
Total Shares
143M
ETF Lock-Up
8.6%
Display Mode
Total Float Impact
8.6%Locked Float

Natera, Inc. (NTRA) exerts measurable gravity on the passive index market, currently representing 4.3% of the ARK Genomic Revolution ETF (ARKG) and 2.5% of the IBB (IBB). Across 14 tracked ETFs, approximately 12M shares (8.6% of float) are held by passive funds and rarely trade on the open market. As passive ownership grows, index inclusion changes may increasingly drive price discovery.

Float lock-up computed from 14 ETFs tracked by SecuritiesDB. Actual passive ownership is higher (includes mutual funds, pension funds, etc.).

NTRA Institutional Volume Profile

252-day volume distribution by price level. The Point of Control (POC) marks the price where the most institutional volume transacted — an implicit support/resistance floor.

TICKER
NTRA
PRICE
$212.73
FLOOR (POC)
$197.20
STRENGTH
High
$135$141$147$154$1608%$16611%$172$179$185$191$197POC 13%$20310%$2109%$212.73$216$222$228$2357%$241$247$253
Focus Zone
Point of Control (POC) Support (below price) Resistance (above price) Current Price

The highest-volume price zone for Natera, Inc. over the past year sits near $197.20 (13% of 252-day volume). The current price of $212.73 trades 7.9% above this institutional floor — a sign of upside momentum, though a pullback to the POC zone is a common reversion target. The highly concentrated volume profile (13% at POC) indicates strong consensus on fair value — institutional participants have repeatedly transacted near this price.

Volume Profile computed from 252 trading days of OHLCV data. Volume allocated to price bins proportionally based on daily high-low range. Not investment advice.

Fails-to-Deliver (FTD) History

SEC-reported settlement failures. Elevated FTDs can indicate high short-selling pressure, operational settlement issues, or naked shorting activity.

DateFailed SharesClose PriceNotional Value
2026-04-24571$201.14$114,850.94
2026-04-21516$207.74$107,193.84
2026-04-17967$196.11$189,638.37
2026-04-15622$214.64$133,506.08
2026-04-08188$209.27$39,342.76
2026-04-0621$207.98$4,367.58
2026-03-3183,324$186.84$15.6M
2026-03-246$200.09$1,200.54
2026-03-11834$198.95$165,924.3
2026-03-027,751$208.04$1.6M
2026-02-1012$210.58$2,526.96
2026-01-293$235.93$707.79
2026-01-2186$234.85$20,197.1
2026-01-1553$239.19$12,677.07
2026-01-121,238$234.31$290,075.78
2026-01-091,287$239.56$308,313.72
2026-01-081,154$254.40$293,577.6
2026-01-067,421$237.42$1.8M
2025-12-317,408$229.98$1.7M
2025-12-291$233.74$233.74
2025-12-2435,188$235.40$8.3M
2025-12-233,326$235.57$783,505.82
2025-12-2243,790$231.96$10.2M
2025-12-19507$224.74$113,943.18
2025-12-18487$225.49$109,813.63
2025-12-103$235.53$706.59
2025-12-0425$238.21$5,955.25
2025-11-2526,264$238.58$6.3M
2025-11-245,708$230.63$1.3M
2025-11-2112,514$225.55$2.8M

Source: SEC Regulation SHO FTD data. Data is reported with a ~30 day delay. High FTD quantities relative to average daily volume may indicate settlement stress.

Price Correlations

Statistical correlation of daily returns with other stocks. High correlations indicate stocks that move together; negative correlations can offer diversification.

Peer252-Day (1Y)126-Day (6M)Direction
WTGXXNaNNaN
GH0.4810.487Moderate
VCYT0.4610.463Moderate
PSNL0.4350.451Moderate
TEM0.4320.505Moderate
ADPT0.4200.469Moderate
CDNA0.4130.468Moderate
PACB0.4080.509Moderate
TRMB0.4020.452Moderate
MS0.4000.408Moderate

Pearson correlation of daily log returns. 252d ≈ 1 trading year. Computed from price history. Not investment advice.

Compare NTRA to Peers

Quant metrics computed deterministically from financial statements and price data. Updated: 2026-06-02.

SecuritiesDB provides programmatic data aggregation for informational purposes only. None of the metrics, summaries, or algorithmic flags constitute a recommendation to buy or sell any security.