Healthcare

Beam Therapeutics Inc. (BEAM)

$28.96
-7.00%
$3.4B
Market Cap
P/E Ratio
2.26
Beta
Dividend Yield
Piotroski 3/9Altman Z 5.5 Safe

Quantitative Summary

Deterministic

Below-average fundamentals indicated by Piotroski score of 3/9.

Generated deterministically from quant metrics and financial statements. Not a recommendation.

Algorithmic Teardown

AI-Generated

Beam Therapeutics presents a stark dichotomy between aggressive top-line expansion and deteriorating fundamental efficiency. While revenue growth accelerates at 120% year-over-year, the company operates with a severe net margin contraction of -57.2%, driving both ROIC to -21.9% and DuPont-decomposed ROE to -6.5%. This negative return on equity is mechanically driven by low asset turnover (0.09x) rather than leverage, which sits at a conservative 1.20x multiplier. The Piotroski F-Score of 3/9 signals weak financial health relative to peers, yet the Altman Z-Score of 5.5 suggests the balance sheet currently avoids immediate insolvency risks despite these operational headwinds.

Valuation metrics reflect significant market optimism regarding future commercialization potential rather than current earnings power. With no positive net income, traditional P/E comparisons are inapplicable; however, trading at a sector average multiple of 37.5x implies the market is pricing in substantial normalized profitability and growth duration that has not yet materialized on an accrual basis. The disconnect between current cash-burning dynamics and high valuation multiples creates a scenario where any deviation from the projected revenue trajectory could precipitate a sharp re-rating, as historical performance fails to justify the premium assigned by investors expecting a successful transition to positive cash flows.

Risk-adjusted return factors highlight specific exposure profiles within the equity universe. The stock exhibits strong momentum characteristics with an annual Fama-French Alpha of 17.18%, outperforming its risk-free benchmark significantly over the measured period. Conversely, factor tilts reveal substantial vulnerability: a Value Factor (HML) of -0.914 indicates heavy growth weighting, while a Profitability Factor (RMW) of -1.817 underscores severe weakness in earnings generation relative to value and profitable peers. This risk profile is compounded by insider activity showing $3,767,883 net selling over the last 90 days, suggesting internal stakeholders may be positioning defensively or reallocating capital despite the stock's recent alpha performance.

Generated by LLM from quantitative data inputs. May contain inaccuracies. Not investment advice.

Price Chart with Moving Averages

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SMA 50 SMA 200

Technical Setup

AI Generated

The current technical landscape for Beam Therapeutics Inc. suggests a complex interplay between price action and institutional positioning, though specific moving average crossovers are not detailed in the provided data to definitively confirm trend direction. Without explicit signals regarding short-term versus long-term moving average relationships, it remains unclear whether larger market participants are actively accumulating shares or reducing exposure at these levels. The stock's proximity to key psychological thresholds often serves as a focal point for institutional algorithms, potentially leading to increased volatility if significant order flow emerges near the $27.93 mark. Volume trends remain an ambiguous variable in this snapshot, lacking specific data points that would indicate whether trading activity is supporting or contravening recent price movements. In healthcare equities, particularly those with biotech characteristics like BEAM, volume spikes often precede major shifts in institutional sentiment, yet the absence of concrete figures here prevents a clear assessment of capital flow dynamics. The lack of definitive crossover confirmation implies that while some players may be testing support or resistance zones, no overwhelming consensus on direction is currently visible through these standard technical lenses alone.

RSI (14)
SMA 50
SMA 200

Quant Health Deep Dive

3/9
Piotroski F-Score
Weak — below-average operational and profitability metrics
5.5
Altman Z-Score
Safe Zone — above 3.0 threshold per academic model. Thresholds: >3 safe, 1.8–3 grey, <1.8 distress.

Profitability & Value Creation

-57.2%
Net Margin
-21.9%
ROIC
+120.0%
Revenue Growth (YoY)
+78.8%
Earnings Growth (YoY)
-360.0M
Free Cash Flow

DuPont Analysis — ROE Decomposition

Breaking down Return on Equity to see how the company generates its ROE — efficiency, margins, or leverage.

-57.2%
Net Profit Margin
NI ÷ Revenue
×
0.09x
Asset Turnover
Revenue ÷ Assets
×
1.20x
Equity Multiplier
Assets ÷ Equity
=
-6.5%
Return on Equity
Balanced ROE composition across margins, turnover, and leverage.

Balance Sheet Health

0.20x
Debt / Equity
13.09x
Current Ratio
-14.41%
FCF Yield
-361.4M
EBITDA

Insider Activity (Last 90 Days)

Net Insider Flow
-$4M
Net Selling
0
Buy Transactions
8
Sale Transactions
2026-02-24CIARAMELLA GIUSEPPESold 4/8 qtrsSale$1M
2026-02-24CIARAMELLA GIUSEPPESold 4/8 qtrsGrant$595,000
2026-01-30EVANS JOHN M.Sold 6/8 qtrsSale$1M
2026-01-30EVANS JOHN M.Sold 6/8 qtrsGrant$33,500
2026-01-22BELLON CHRISTINESold 6/8 qtrsSale$46,614

Open-market buys vs sells by company insiders. Source: yfinance.

Earnings Surprise History

Q4
✗ Miss
Est: $-1.17
Act: $-1.24
-5.9%
Q3
✓ Beat
Est: $-1.09
Act: $-1.00
+8.4%
Q2
✗ Miss
Est: $-1.01
Act: $-1.10
-9.0%
Q1
✓ Beat
Est: $-1.12
Act: $2.33
+309.0%

EPS estimates vs actuals for the most recent reported quarters. Source: yfinance.

Risk Profile

75.3%
Annual Volatility
1.12
Sharpe (1Y)
0.30
Sharpe (3Y)
-67.7%
Max Drawdown (3Y)
-89.1%
Max Drawdown (5Y)

Sharpe = risk-adjusted return (higher is better). Max drawdown = largest peak-to-trough decline. 1,200+ trading days.

Underwater (Drawdown from Peak)

How far below the all-time high the price has been over time. Deeper = more pain for holders.

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Rolling 60-Day Beta vs S&P 500 (VOO)

How the stock's sensitivity to market moves changes over time. β > 1 = more volatile than the market.

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Rolling Beta Market (β = 1.0)

Fama-French 5-Factor Exposure

Academic factor model decomposition — what's really driving this stock's returns.

0.92
Market β
Mkt-RF
+2.637
Size (SMB)
Small-cap tilt
-0.914
Value (HML)
Growth tilt
-1.817
Profit (RMW)
Weak
+0.563
Invest (CMA)
Conservative
Alpha (annual): +17.18%
R²: 42.1%of variance explained by 5 factors

Fama-French 5-Factor Model. Data: Kenneth French Data Library. Regression over 3 years of daily returns.

Fundamentals

-6.9
Forward P/E
PEG Ratio
2.81
Price/Book
2M
Avg Volume
$36.44
52W High
$15.60
52W Low
64%
52W Range Position

Passive Flow Attribution

ETF Draft Effect
$382M
Tracked Passive Exposure
6
ETFs Holding BEAM
0.43%
Avg Weight in ETFs
$88B
Total ETF AUM

When investors buy or sell ETFs like ARKG or ARKK, the fund manager is mechanically forced to buy or sell BEAM shares regardless of Beam Therapeutics Inc.'s individual fundamentals. We estimate $382M of passive capital is structurally linked to BEAM through 6 tracked ETFs. Passive flows have a limited but growing influence on BEAM's daily trading dynamics.

Passive exposure = Σ (ETF AUM × stock weight in ETF) across 6 tracked ETFs. Actual passive ownership is larger (includes mutual funds). Not investment advice.

ETF Contagion Visualizer

Simulate a price drop in Beam Therapeutics Inc. to visualize passive redemption contagion across ETFs and collateral stocks.

BEAM Shock
-0%
Est. Passive Redemption
$0
Systemic Risk
STABLE
BEAMEpicenterVBKETFVHTETFVTWOETFCRSPLow RiskTEMHigh RiskTWSTLow RiskTSLALow RiskTXGLow Risk
BEAM Price Drop (%)0

If Beam Therapeutics Inc. (BEAM) experiences a significant drawdown, ETF redemptions can create collateral selling pressure on co-held stocks. Our model identifies CRISPR THERAPEUTICS AG (CRSP) as the most exposed collateral stock, sharing 3 ETFs with BEAM. This is the "Passive Contagion" effect described in the Inelastic Market Hypothesis.

Contagion model based on shared ETF exposure and constituent weights across 6 tracked ETFs. Estimated selling pressure is a simplified model — actual impact depends on market liquidity, ETF redemption mechanics, and market-maker activity.

BEAM Ownership Dynamics

Passive funds hold 1 in every 7 BEAM shares, reducing daily market volatility.

Ticker
BEAM
Total Shares
103M
ETF Lock-Up
13.8%
Display Mode
Total Float Impact
13.8%Locked Float

Beam Therapeutics Inc. (BEAM) exerts measurable gravity on the passive index market, currently representing 4.8% of the ARK Genomic Revolution ETF (ARKG) and 2.8% of the ARK Innovation ETF (ARKK). Across 6 tracked ETFs, approximately 14M shares (13.8% of float) are held by passive funds and rarely trade on the open market. This level of passive ownership means index rebalances can create outsized volume events.

Float lock-up computed from 6 ETFs tracked by SecuritiesDB. Actual passive ownership is higher (includes mutual funds, pension funds, etc.).

BEAM Institutional Volume Profile

252-day volume distribution by price level. The Point of Control (POC) marks the price where the most institutional volume transacted — an implicit support/resistance floor.

TICKER
BEAM
PRICE
$28.96
FLOOR (POC)
$27.58
STRENGTH
Medium
$16$179%$18$19$20$217%$22$23$247%$268%$278%$28POC 9%$29$28.96$30$31$32$33$34$35$36
Focus Zone
Point of Control (POC) Support (below price) Resistance (above price) Current Price

The highest-volume price zone for Beam Therapeutics Inc. over the past year sits near $27.58 (9% of 252-day volume). The current price of $28.96 trades 5.0% above this institutional floor — a sign of upside momentum, though a pullback to the POC zone is a common reversion target.

Volume Profile computed from 252 trading days of OHLCV data. Volume allocated to price bins proportionally based on daily high-low range. Not investment advice.

Fails-to-Deliver (FTD) History

SEC-reported settlement failures. Elevated FTDs can indicate high short-selling pressure, operational settlement issues, or naked shorting activity.

DateFailed SharesClose PriceNotional Value
2026-05-1117$32.32$549.44
2026-05-0821,010$31.47$661,184.7
2026-05-0720$32.34$646.8
2026-04-3028$29.38$822.64
2026-04-2913,405$30.56$409,656.8
2026-04-242,005$30.16$60,470.8
2026-04-202,671$31.39$83,842.69
2026-04-173,138$30.33$95,175.54
2026-04-1612,132$30.68$372,209.76
2026-04-15124$30.30$3,757.2
2026-04-062,863$24.66$70,601.58
2026-03-3021,273$22.19$472,047.87
2026-03-1845$25.83$1,162.35
2026-03-175$25.49$127.45
2026-03-1021,697$27.62$599,271.14
2026-03-096,507$26.54$172,695.78
2026-02-261,574$29.61$46,606.14
2026-02-1288$25.99$2,287.12
2026-02-06840$24.73$20,773.2
2026-02-0511,989$26.95$323,103.55
2026-02-02153$27.62$4,225.86
2026-01-211,300$30.97$40,261
2026-01-20678$31.22$21,167.16
2025-12-245,845$27.77$162,315.65
2025-12-233,435$27.92$95,905.2
2025-12-2239,086$26.57$1.0M
2025-12-055$28.91$144.55
2025-12-0473,870$26.74$2.0M
2025-12-01156$25.33$3,951.48
2025-11-28437$25.03$10,938.11

Source: SEC Regulation SHO FTD data. Data is reported with a ~30 day delay. High FTD quantities relative to average daily volume may indicate settlement stress.

Price Correlations

Statistical correlation of daily returns with other stocks. High correlations indicate stocks that move together; negative correlations can offer diversification.

Peer252-Day (1Y)126-Day (6M)Direction
WTGXXNaNNaN
CRSP0.6730.723Moderate
NTLA0.6150.584Moderate
PRME0.5820.651Moderate
RXRX0.5490.547Moderate
ABSI0.4830.479Moderate
SDGR0.4720.497Moderate
TWST0.4670.481Moderate
PACB0.4300.470Moderate
NRIX0.4110.289Moderate

Pearson correlation of daily log returns. 252d ≈ 1 trading year. Computed from price history. Not investment advice.

Compare BEAM to Peers

Quant metrics computed deterministically from financial statements and price data. Updated: 2026-06-02.

SecuritiesDB provides programmatic data aggregation for informational purposes only. None of the metrics, summaries, or algorithmic flags constitute a recommendation to buy or sell any security.