Healthcare

AstraZeneca PLC (AZN)

$177.45
-1.26%
$287.9B
Market Cap
27.9
P/E Ratio
0.22
Beta
1.70%
Dividend Yield
Piotroski 7/9Altman Z 3.9 SafeROIC−WACC +5.6%

Quantitative Summary

Deterministic

At 27.9x earnings — a 57% discount to the sector average of 65.2x — AZN is in the lower valuation range. Financial health metrics are strong: Piotroski 7/9, Altman Z 3.9 (above 3.0 safe zone threshold). DCF fair value of $133 implies 34% downside based on model assumptions.

Generated deterministically from quant metrics and financial statements. Not a recommendation.

Algorithmic Teardown

AI-Generated

The fundamental economics of this pharmaceutical entity demonstrate a robust quality profile, anchored by an ROIC-WACC spread of +7.1% that indicates significant value creation potential relative to the cost of capital. The DuPont decomposition reveals that the 21.0% return on equity is primarily margin-driven at 17.4%, supported by moderate asset turnover and financial leverage; however, the Profitability Factor (RMW) score of -0.176 suggests recent deterioration in this specific dimension despite strong historical margins. Creditworthiness remains solid with an Altman Z-Score of 3.7, while a Piotroski F-Score of 7/9 signals overall financial strength, though the weak profitability delta warrants monitoring for margin compression risks.

Valuation metrics present a mixed picture where the current P/E of 31.2x trades at a premium to historical norms and likely exceeds sector averages given the implied long-term free cash flow growth rate of only 4.8%. The DCF model, which incorporates these low-growth assumptions, yields a fair value estimate that implies merely 2.1% upside from current levels, suggesting the market is pricing in sustained high returns rather than aggressive expansion. This disconnect between the company's strong ROIC generation and its muted implied growth trajectory indicates that investors are currently demanding a premium for quality while simultaneously discounting future scalability.

Risk-reward dynamics appear skewed by conflicting factor exposures: the stock exhibits substantial Fama-French alpha of 10.16%, indicating superior risk-adjusted performance over time, yet it registers as neutral on value and weak on profitability factors. With no insider flow activity detected in the last ninety days, there is a lack of directional signaling from management regarding future catalysts or capital allocation shifts. The combination of high valuation multiples against stagnant implied growth creates an environment where downside protection relies heavily on margin durability rather than multiple expansion.

Generated by LLM from quantitative data inputs. May contain inaccuracies. Not investment advice.

DCF Sandbox

Interactive
Market Price
$177.45
Fair Value
$134
Implied Upside
-24.5%
$134IMPLIED FAIR VALUEOVERVALUEDOVERUNDER
Growth Rate (Y1–5)8%
-10%20%50%
Discount Rate (WACC)7.7%
5%12.5%20%

5-year two-stage DCF. Terminal growth 3%. Default sliders match the pre-computed base case. Drag to explore scenarios. Not investment advice.

Reverse DCFMarket-Implied
10.0%annual FCF growth priced in at $177.45

The growth rate the market implicitly expects over the next 10 years to justify today's price. Compare with historical growth of 9% YoY revenue.

Sensitivity Matrix

TG ↓ / WACC →6%7.7%9.7%
2%$165$111$79
3%$217$133$89
4%$320$166$103

Center = base case. Green = >10% upside, Red = >10% downside vs $177.45.

Pre-computed DCF: WACC=7.7%, terminal growth 3%. Fair value $133 (-34.3%). Not investment advice.

Valuation Context

27.9x
AZN P/E
65.2x
Sector Avg
21.9x
5Y Avg P/E
-57%
vs Sector

Currently trading 42% above its 5-year average P/E of 21.9x.

Price Chart with Moving Averages

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SMA 50 SMA 200

Technical Setup

AI Generated

AstraZeneca PLC is currently trading at $181.58, presenting a specific snapshot within its technical framework that warrants observation regarding relative value positioning. Without access to the precise location of the Simple Moving Average (SMA) envelope boundaries or recent volatility metrics, it remains impossible to definitively characterize whether this price point represents an extreme deviation from historical norms or sits comfortably near the mean. The absence of data indicating how far the current valuation diverges from its moving average limits any immediate assessment of potential mean-reversion dynamics; consequently, one cannot determine if the stock is statistically overextended due for a pullback or undervalued relative to recent trends and poised for upward correction. In the context of healthcare sector analysis, this single data point serves merely as an anchor rather than a comprehensive signal. Determining whether $181.58 constitutes a zone where price discovery might reverse requires knowledge of the surrounding statistical distribution provided by the SMA bands. If future disclosures reveal that this level lies significantly outside the upper or lower envelope limits, it would theoretically suggest heightened probability for a return toward equilibrium levels typical of mean-reversion strategies. Conversely, if the current price resides near the center of the calculated range, the implication would be continued stability rather than an impending directional shift based on statistical extremes alone. Ultimately, the technical narrative here is incomplete without the envelope parameters that define normal trading ranges versus anomalous deviations. Investors must await further confirmation regarding the distance between $181.5

RSI (14)
SMA 50
SMA 200

Quant Health Deep Dive

7/9
Piotroski F-Score
Strong — high operational efficiency and profitability signals
3.9
Altman Z-Score
Safe Zone — above 3.0 threshold per academic model. Thresholds: >3 safe, 1.8–3 grey, <1.8 distress.

Profitability & Value Creation

81.9%
Gross Margin
17.4%
Net Margin
13.3%
ROIC
7.7%
WACC
ROIC − WACC Spread: +5.6%— Positive value creation spread.
+8.6%
Revenue Growth (YoY)
+45.3%
Earnings Growth (YoY)
8.7B
Free Cash Flow
57%
FCF Payout Ratio

✅ Conservative payout — room for dividend increases.

DuPont Analysis — ROE Decomposition

Breaking down Return on Equity to see how the company generates its ROE — efficiency, margins, or leverage.

17.4%
Net Profit Margin
NI ÷ Revenue
×
0.51x
Asset Turnover
Revenue ÷ Assets
×
2.34x
Equity Multiplier
Assets ÷ Equity
=
21.0%
Return on Equity
✅ ROE driven primarily by strong profit margins — a sign of pricing power.

Balance Sheet Health

1.34x
Debt / Equity
0.94x
Current Ratio
8.7x
Interest Coverage
1.0x
Net Debt / EBITDA
2.59%
FCF Yield
19.5B
EBITDA

Dividend History

$2.1530
Latest Dividend
$3.13
2025 Total
+5.4%
YoY Growth
2 yrs
Consecutive Increases
Annual Dividends per Share
$0.49
2006
$1.75
2007
$1.90
2008
$2.09
2009
$2.41
2010
$2.70
2011
$2.85
2012
$2.80
2013
$2.80
2014
$2.80
2015
$2.80
2016
$2.80
2017
$2.80
2018
$2.80
2019
$2.80
2020
$2.80
2021
$2.90
2022
$2.90
2023
$2.97
2024
$3.13
2025
$2.15
2026
DateAmountChange
2026-02-19$2.1530+109.0%
2025-08-08$1.0300-51.0%
2025-02-21$2.1000+110.0%
2024-08-09$1.0000-49.2%
2024-02-22$1.9700+111.8%
2023-08-10$0.9300-52.8%
2023-02-23$1.9700+111.8%
2022-08-11$0.9300-52.8%
2022-02-24$1.9700+118.9%
2021-08-12$0.9000-52.6%
2021-02-25$1.9000+111.1%
2020-08-13$0.9000-52.6%
Stock Splits
2026-02-02: 0.5:12015-07-27: 2:11998-04-08: 3:1

Dividend and split data from SEC filings and market data. Amounts are per share, not adjusted for splits. Source: yfinance.

Risk Profile

23.8%
Annual Volatility
1.61
Sharpe (1Y)
0.48
Sharpe (3Y)
-27.9%
Max Drawdown (3Y)
-27.9%
Max Drawdown (5Y)

Sharpe = risk-adjusted return (higher is better). Max drawdown = largest peak-to-trough decline. 1,200+ trading days.

Underwater (Drawdown from Peak)

How far below the all-time high the price has been over time. Deeper = more pain for holders.

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Rolling 60-Day Beta vs S&P 500 (VOO)

How the stock's sensitivity to market moves changes over time. β > 1 = more volatile than the market.

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Rolling Beta Market (β = 1.0)

Fama-French 5-Factor Exposure

Academic factor model decomposition — what's really driving this stock's returns.

0.39
Market β
Mkt-RF
-0.121
Size (SMB)
Large-cap tilt
+0.047
Value (HML)
Neutral
-0.176
Profit (RMW)
Weak
+0.507
Invest (CMA)
Conservative
Alpha (annual): +10.16%
R²: 8.8%of variance explained by 5 factors

Fama-French 5-Factor Model. Data: Kenneth French Data Library. Regression over 3 years of daily returns.

Fundamentals

23.1
Forward P/E
1.43
PEG Ratio
6.08
Price/Book
2M
Avg Volume
$212.71
52W High
$137.22
52W Low
53%
52W Range Position

Passive Flow Attribution

ETF Draft Effect
$8.5B
Tracked Passive Exposure
8
ETFs Holding AZN
0.74%
Avg Weight in ETFs
$1.2T
Total ETF AUM

When investors buy or sell ETFs like VGK or VSGX, the fund manager is mechanically forced to buy or sell AZN shares regardless of AstraZeneca PLC's individual fundamentals. We estimate $8.5B of passive capital is structurally linked to AZN through 8 tracked ETFs. This substantial passive exposure means that ETF inflows and outflows — not company fundamentals — can dominate daily volume on this stock.

Passive exposure = Σ (ETF AUM × stock weight in ETF) across 8 tracked ETFs. Actual passive ownership is larger (includes mutual funds). Not investment advice.

ETF Contagion Visualizer

Simulate a price drop in AstraZeneca PLC to visualize passive redemption contagion across ETFs and collateral stocks.

AZN Shock
-0%
Est. Passive Redemption
$0
Systemic Risk
STABLE
AZNEpicenterVXUSETFVEAETFVEUETFASMLLow RiskSMSNUnknown2330UnknownTSMLow Risk005930Unknown
AZN Price Drop (%)0

If AstraZeneca PLC (AZN) experiences a significant drawdown, ETF redemptions can create collateral selling pressure on co-held stocks. Our model identifies ASML Holding NV (ASML) as the most exposed collateral stock, sharing 3 ETFs with AZN. This is the "Passive Contagion" effect described in the Inelastic Market Hypothesis.

Contagion model based on shared ETF exposure and constituent weights across 8 tracked ETFs. Estimated selling pressure is a simplified model — actual impact depends on market liquidity, ETF redemption mechanics, and market-maker activity.

AZN Ownership Dynamics

Passive funds hold 1 in every 33 AZN shares, reducing daily market volatility.

Ticker
AZN
Total Shares
1.6B
ETF Lock-Up
3.0%
Display Mode
Total Float Impact
3.0%Locked Float

AstraZeneca PLC (AZN) exerts measurable gravity on the passive index market, currently representing 1.8% of the VGK (VGK) and 1.0% of the VSGX (VSGX). Across 8 tracked ETFs, approximately 47M shares (3.0% of float) are held by passive funds and rarely trade on the open market. As passive ownership grows, index inclusion changes may increasingly drive price discovery.

Float lock-up computed from 8 ETFs tracked by SecuritiesDB. Actual passive ownership is higher (includes mutual funds, pension funds, etc.).

AZN Institutional Volume Profile

252-day volume distribution by price level. The Point of Control (POC) marks the price where the most institutional volume transacted — an implicit support/resistance floor.

TICKER
AZN
PRICE
$177.45
FLOOR (POC)
$185.93
STRENGTH
High
$137$141$1447%$148$152$156$159$163$1677%$171$175$17810%$177.45$1829%$186POC 16%$1907%$193$197$201$205$209
Focus Zone
Point of Control (POC) Support (below price) Resistance (above price) Current Price

The highest-volume price zone for AstraZeneca PLC over the past year sits near $185.93 (16% of 252-day volume). The current price of $177.45 sits 4.6% below the POC — suggesting potential mean-reversion upside if institutional demand reasserts at this level. The highly concentrated volume profile (16% at POC) indicates strong consensus on fair value — institutional participants have repeatedly transacted near this price.

Volume Profile computed from 252 trading days of OHLCV data. Volume allocated to price bins proportionally based on daily high-low range. Not investment advice.

AZN Capital Efficiency

How efficiently does AstraZeneca PLC convert operating profits into free cash? The FCF Conversion ratio measures the gap between accounting earnings and real cash generation.

Free Cash Flow
$8.7B
EBITDA
$19.5B
FCF Conversion
44%
Reinvestment Rate
56%
44% of EBITDA → Free Cash
0% (cash burn)25% (low)50% (efficient)100% (pure cash)
ROIC
13.3%
ROIC − WACC Spread
5.6%

AstraZeneca PLC converts 44% of its EBITDA into free cash flow, a healthy conversion rate indicating efficient capital management — the business generates substantial cash after reinvestment. The 56% reinvestment rate signals aggressive capacity expansion. The positive ROIC-WACC spread of 5.6% confirms that reinvested capital creates shareholder value.

Capital efficiency = Free Cash Flow ÷ EBITDA. Reinvestment = (EBITDA − FCF) ÷ EBITDA. Metrics from latest annual filings. Not investment advice.

Fails-to-Deliver (FTD) History

SEC-reported settlement failures. Elevated FTDs can indicate high short-selling pressure, operational settlement issues, or naked shorting activity.

DateFailed SharesClose PriceNotional Value
2026-05-1343,992$184.54$8.1M
2026-05-122,193$181.86$398,818.98
2026-05-1143$182.85$7,862.55
2026-05-07135$184.92$24,964.2
2026-05-063,469$181.24$628,721.56
2026-05-04444$184.74$82,024.56
2026-04-2413$192.30$2,499.9
2026-04-20800$204.80$163,840
2026-04-158,537$204.38$1.7M
2026-04-13453$204.03$92,425.59
2026-04-103$204.99$614.97
2026-04-091$204.27$204.27
2026-04-0650$203.49$10,174.5
2026-04-015,145$197.22$1.0M
2026-03-3121,241$193.88$4.1M
2026-03-25101$185.78$18,763.78
2026-03-243,969$184.07$730,573.83
2026-03-238$183.60$1,468.8
2026-03-041,409$201.76$284,279.84
2026-03-0333$203.73$6,723.09
2026-03-022,442$208.45$509,034.9
2026-02-2710$203.98$2,039.8
2026-02-2659$205.79$12,141.61
2026-02-23200$204.20$40,840
2026-02-203,902$208.62$814,035.24
2026-02-195,570$208.67$1.2M
2026-02-171$205.55$205.55
2026-02-1350$204.52$10,226
2026-02-12345$204.76$70,642.2
2026-02-111,996$193.40$386,026.4

Source: SEC Regulation SHO FTD data. Data is reported with a ~30 day delay. High FTD quantities relative to average daily volume may indicate settlement stress.

Price Correlations

Statistical correlation of daily returns with other stocks. High correlations indicate stocks that move together; negative correlations can offer diversification.

Peer252-Day (1Y)126-Day (6M)Direction
WTGXXNaNNaN
MRK0.5890.423Moderate
PFE0.5370.415Moderate
BMY0.5210.342Moderate
CH00120320480.5190.558Moderate
A0.4860.364Moderate
DHR0.4720.274Moderate
AMGN0.4680.345Moderate
ABBV0.4650.275Moderate
TMO0.4430.168Moderate

Pearson correlation of daily log returns. 252d ≈ 1 trading year. Computed from price history. Not investment advice.

Compare AZN to Peers

Quant metrics computed deterministically from financial statements and price data. Updated: 2026-06-02.

SecuritiesDB provides programmatic data aggregation for informational purposes only. None of the metrics, summaries, or algorithmic flags constitute a recommendation to buy or sell any security.